Neurological deterioration in Parkinson’s disease (PD) and resulting motor dysfunction arises from Lewy body formation and dopaminergic neuronal death in the substantia nigra.
Two factors contributing to PD-related apoptosis and subsequent motor dysfunction involve improper cellular metabolism of reactive oxygen species (ROS) and impaired mitochondrial functionality.
The co-factor Nicotinamide Adenine Dinucleotide (NAD +), a reduction of which has been implicated in the development of neurodegenerative disease, is a critical player in maintaining cellular redox metabolism and mitochondrial function.
We present a case study of a PD patient who has become near asymptomatic through the use of intravenous (I.V.) NAD +. This report documents the patient’s initial symptom changes while receiving I.V. NAD + over the course of eight treatment days, with two non-treatment days in between.
The treatment entailed 1500 mg. I.V. NAD + on day one, 1000 mg. I.V. NAD + on day two, and 750 mg. I.V. NAD + on day three. Symptoms were documented by medical staff for the next two days of non-treatment.
Following this, 750 mg. I.V. NAD + was administered on treatment days four and five, 500 mg. I.V. NAD + on treatment days six and seven, and 750 mg. I.V. NAD + on treatment day eight. Over the course of treatment, the patient’s hand tremors decreased to a mild level, permitting coordinated use of a pen and utensils. Hand tremors were absent on days one and six.
Visual hallucinations were absent on days two through seven. To maintain tremors at a tolerable level, aftercare involved I.V. NAD + every four to six weeks, with a daily regimen of 300 mg/ml NAD + nasal spray. Moreover, the patient discontinued PD-related medication, thereby preventing visual hallucination side effects. Although more research on NAD + in clinical use is needed, the evidence obtained from these symptom improvements indicates NAD + as having the potential for clinical use in at least a subset of PD sufferers.
Unlike other clinics offering “menus”, DripDok works with patients to establish an individual protocol based on their personal health history and data.
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