NAD+ IV Therapy Bali | NMN IV · Hybrid NMN
NAD+ IV Therapy Bali | NMN IV · Hybrid NMN
DRIPDOK IS THE FIRST CLINIC IN SOUTHEAST ASIA TO OFFER NAD+ IV THERAPY AND THE SECOND CLINIC IN THE WORLD TO OFFER NMN IV — INTRAVENOUS NICOTINAMIDE MONONUCLEOTIDE, A DIRECT NAD+ BIOSYNTHESIS PRECURSOR AT THE STEP IMMEDIATELY PROXIMAL TO NAD+ ITSELF. NAD+ FUNCTIONS AS THE ESSENTIAL COENZYME IN OVER 500 ENZYMATIC REACTIONS, INCLUDING SIRTUIN ACTIVATION (SIRT1–3, SIRT5), PARP-MEDIATED DNA REPAIR, CD38-DEPENDENT CALCIUM SIGNALLING, AND THE COMPLETE MITOCHONDRIAL ELECTRON TRANSPORT CHAIN (COMPLEX I, III, AND V).
Three protocols available. NAD+ IV (250mg, 500mg, 1000mg): Pure pharmaceutical-grade NAD+ administered over 90–180 minutes with anti-nausea pre-medication. The gold standard for cellular energy restoration, sirtuin activation, and post-viral neurological fatigue. NMN IV (Hybrid): Proprietary Dripdok protocol combining IV NMN with oral NMN co-administration — the only such hybrid protocol in the world — sustaining plasma NMN elevation for 12–16 hours post-infusion. Hybrid NMN: Dripdok-exclusive oral NMN protocol combining Uthever® NMN with resveratrol and pterostilbene for optimised SIRT1 co-activation.
All NAD+ and NMN protocols are physician-prescribed and nurse-administered. Flush symptoms (flushing, chest tightness) are pre-screened and managed with slow-rate infusion and antihistamine pre-dosing where indicated. Available across all Bali areas. 24–48 hours advance notice required for cold-chain prep.
Session at a Glance
mL
IV
min
RN
Rx
24h
MD
SVC
From $125 USD
NAD+ & NMN IV THERAPY
NAD+ IV Therapy Bali | NMN IV · Hybrid NAD Protocol
The first clinic in Southeast Asia to offer NAD+ IV therapy and the second worldwide to administer NMN intravenously. A precision cellular energy protocol — physician-reviewed, nurse-administered, delivered to your location across Bali.
250–1000 mL
Infusion volume per session
100%
Bioavailability via IV delivery
90–180 min
Typical session duration
NAD⁺ PRECURSOR MATRIX
NAD⁺ · NMN · Hybrid Protocol Formulation
Each component is selected for physiological relevance and enzymatic function — not marketing appeal.
NAD⁺
Nicotinamide Adenine Dinucleotide (USP 797)
Nicotinamide adenine dinucleotide at therapeutic IV dose (250–1000mg). Acts as the direct substrate for sirtuin activation (SIRT1–7), PARP-mediated DNA repair, and CD38-dependent calcium signalling. Bypasses all oral absorption limitations.
NMN
Nicotinamide Mononucleotide (Slc12a8)
Nicotinamide mononucleotide administered via the Slc12a8 transporter pathway — intracellular delivery bypassing extracellular hydrolysis. No adenosine cascade, no flushing response. Second clinic globally to offer IV NMN.
B-Vit
B-Complex + Soluvit (Myers Base Incl.)
Soluvit B-complex base provides the complete B-vitamin cofactor matrix. Thiamine, riboflavin, pyridoxine, and cyanocobalamin support NAD biosynthesis via the Preiss-Handler and salvage pathways — optimising intracellular NAD+ utilisation post-repletion.
B3
Nicotinamide (Direct NAD⁺ Precursor)
Nicotinamide (B3) is a direct NAD+ precursor via the salvage pathway. Included as a cofactor rather than primary substrate — supports endogenous NAMPT-mediated NAD recycling and reduces the metabolic load on the Preiss-Handler pathway post-infusion.
Mg/Zn
Magnesium & Zinc (CD38 Cofactors)
Magnesium sulphate (MgSO₄) and zinc are essential cofactors for CD38 — the primary NAD-consuming enzyme. Adequate Mg and Zn levels reduce competitive NAD depletion by CD38, extending the therapeutic window of restored NAD+ concentrations.
B5
Dexpanthenol (CoA Synthesis Support)
Dexpanthenol (provitamin B5) is converted to pantothenic acid for Coenzyme A synthesis — essential for fatty acid oxidation, acetylcholine production, and mitochondrial substrate cycling. Supports NAD+ utilisation in the TCA cycle.
CLINICAL BENEFITS
Targeted Cellular Mechanisms
NAD+ IV therapy operates at the molecular level — directly restoring the coenzyme that drives mitochondrial ATP production, sirtuin activation, and DNA repair. Intravenous delivery achieves systemic NAD+ concentrations that oral NMN or NR supplementation cannot replicate at equivalent doses.
01
Sirtuin Activation & DNA Repair
SIRT1 activation requires NAD+ concentrations above a threshold typically unachievable through oral supplementation. IV delivery restores nuclear NAD+ pools directly, enabling SIRT1-mediated histone deacetylation, FOXO3a activation, and p53 pathway regulation.
02
PARP1-Mediated Genomic Integrity
PARP1 (poly-ADP-ribose polymerase) consumes NAD+ to repair single-strand DNA breaks. Replenishing NAD+ via IV restores PARP1 activity without the ceiling imposed by oral bioavailability — supporting DNA damage response kinetics measurably.
03
Mitochondrial ETC Restoration
IV NAD+ restores mitochondrial Complex I, III, and V function by restoring the NAD+/NADH ratio. Electron transport chain efficiency improves across all tissues — particularly measurable in skeletal muscle, neuronal, and hepatic cells with elevated energy demand.
04
CD38 Pathway & Cellular Longevity
CD38 is a major NAD-consuming enzyme upregulated during inflammation and ageing. Adequate intracellular NAD+ combined with zinc cofactors modulates CD38 activity, preserving NAD+ for productive metabolic functions rather than inflammatory signalling.
PROTOCOL COORDINATION
How Each Session is Confirmed
01
Select Date, Time & Service
Submit your preferred service, date, and time. Your Patient Relations (PR) coordinator reviews availability and logistics — PR handles operational scheduling, not clinical decisions.
02
Secure Payment & Intake Form
A payment link is sent via Wise, Stripe, or local transfer. Advance payment is required to confirm the booking. Upon payment, you receive a patient consent and medical intake form to complete.
03
Physician Review & Confirmation
Your physician reviews the intake form for clinical suitability and safety. Once approved, your appointment is formally confirmed. Standard protocols require 24–48 hours advance notice for nurse scheduling and cold-chain preparation.
Begin Your Protocol
Physician-reviewed IV therapy, delivered to your location across Bali. Your Patient Relations team coordinates scheduling, payment, and confirmation. Standard protocols require 24–48 hours advance notice. Request your session below.
Begin Your NAD+ Protocol
Physician-guided NAD+ IV therapy, delivered to your door. Available across Bali — Canggu, Seminyak, Ubud, Kuta, Nusa Dua, and surrounding areas. 24–48 hours advance booking required.
AT-HOME IV THERAPY — BALI
NAD+ IV Therapy Bali
Precision cellular energy restoration via intravenous NAD+ and hybrid NMN infusion. Physician-reviewed, nurse-administered, delivered to your location across Bali.
THE SCIENCE
Mitochondrial Energy Restoration & Longevity Signalling
NAD+ (nicotinamide adenine dinucleotide) is the primary coenzyme driving cellular energy metabolism across all tissues. Intravenous administration delivers NAD+ directly into the bloodstream — rapidly restoring the mitochondrial NAD+/NADH ratio and activating sirtuins (SIRT1–7), the longevity-linked deacetylase enzymes governing DNA repair, inflammation, and metabolic regulation. IV delivery achieves peak bioavailability that oral NMN, NR, or niacinamide cannot match, particularly in individuals with impaired NAD+ biosynthesis.
WHAT'S INSIDE
NAD+ IV Protocol Composition
IV Delivery Base
0.9% Sodium Chloride (Normal Saline) · 250–1000 mL volume titrated by protocol tier · pH-buffered · USP 797 pharmaceutical-grade isotonic base
NAD⁺ Precursor Stack
NAD⁺ (250mg–1000mg, dose-dependent) · NMN (300mg Slc12a8-route, intracellular delivery) · Hybrid dual-precursor at physician-titrated NAD:NMN ratio per bodyweight, age, and biomarker data
Myers Micronutrient Base
B-complex (Soluvit) · Magnesium Sulphate (MgSO₄) · Zinc (CD38 cofactor) · Vitamin C (Ascorbic Acid) · Basic Myers base included every session — optimises the cofactor environment for NAD biosynthesis and utilisation
Component concentrations are clinically determined by protocol. Physician review is required prior to every session. Formulations may be adjusted based on individual intake assessment.
CLINICAL DATA
NAD⁺ Restoration Is Cumulative — Not Immediate
Cellular NAD⁺ levels typically decline with age and metabolic stress. IV restoration follows a progressive accumulation pattern — measurable improvement often requires more than a single infusion.
Directional representation based on published literature. Not a clinical trial result. Individual outcomes vary.
INSIGHT
Sirtuin enzymes — the proteins that regulate DNA repair and metabolic efficiency — require NAD⁺ concentrations that most adults can no longer sustain through biosynthesis alone.
Recent peer-reviewed research has identified that the enzymatic activity of SIRT1 and SIRT3 — two proteins central to mitochondrial health, inflammation regulation, and cellular longevity — is not simply proportional to NAD⁺ levels. Their activation follows a threshold model: below a certain intracellular concentration, activity drops disproportionately. This threshold appears to be consistently above what many individuals maintain through dietary precursors or oral supplementation.
A 2023 study published in a major metabolic biology journal found that IV-delivered NAD⁺ precursors achieved tissue concentrations significantly beyond what oral dosing could replicate — reopening enzymatic pathways that had been functionally dormant. The implication is not just that IV delivery is faster. It may be the only route capable of restoring sirtuin-mediated function in states of significant depletion.
CLINICAL INDICATION
Protocol Suitability
01
Cellular Energy Deficit & Chronic Fatigue. Individuals experiencing persistent fatigue unresponsive to rest, with suspected mitochondrial or metabolic dysfunction. NAD+ IV restores the coenzyme directly required for ATP synthesis across all cellular energy pathways.
02
Longevity Optimisation & Biological Age Management. Those pursuing evidence-informed longevity strategies seeking sirtuin activation, NAD+-dependent DNA repair support, and cellular senescence mitigation. Typically combined with the Myers Cocktail as a sequenced foundation protocol.
03
Neurological Recovery & Cognitive Enhancement. Post-viral fatigue, brain fog, and neurological decline associated with NAD+ depletion. IV delivery achieves CNS-relevant concentrations for cognitive function support, mood regulation, and neuroprotection — physician intake assessment required.
CLINICAL OUTCOMES
Observed Treatment Responses
Energy Restoration & Mitochondrial Output
Reported restoration of sustained cellular energy production via mitochondrial complex I–IV reactivation. Outcomes include resolution of chronic fatigue, improved physical endurance, and elimination of post-exertional malaise in NAD+-depleted individuals.
Cognitive Clarity & Neurological Function
NAD+-dependent sirtuin activation supports neuroprotection, neuroinflammation reduction, and neuronal energy metabolism. Clinically observed improvements in focus, processing speed, and mental clarity — particularly in individuals with post-viral or age-related cognitive decline.
DNA Repair & Cellular Longevity Signalling
PARP1 enzyme activation for DNA strand break repair requires NAD+ as a substrate. NAD+ IV therapy supports the molecular infrastructure for cellular longevity, senescence resistance, and metabolic homeostasis. Individual outcomes vary based on baseline NAD+ depletion and protocol frequency.
Clinical outcomes are individual and may vary based on baseline nutritional status, health history, and protocol frequency. These are reported observations, not therapeutic guarantees. This protocol does not constitute medical treatment for any specific condition. All sessions are physician-reviewed for safety and clinical appropriateness prior to confirmation.
PROTOCOL DESIGN
Optimise Your Stack
NAD⁺ restoration works at the cellular level. Pair it strategically to address mitochondrial function, cognitive performance, and foundational nutrient status together.
UPGRADE YOUR PROTOCOL
NAD⁺ + Exosome Stack
Combine NAD⁺ IV with exosome therapy for a protocol that addresses both energy substrate availability and cellular signalling. The two mechanisms operate on different biological layers — making them synergistic rather than redundant.
View Exosome TherapyPAIR WITH
Myers Cocktail IV
NAD⁺ metabolism depends on adequate cofactors — magnesium, B-vitamins, and zinc among them. The Myers Cocktail provides full-spectrum micronutrient support, creating the environment your cells need to utilise restored NAD⁺ most effectively.
Explore Myers CocktailNOT SURE WHERE TO START?
Begin With the Foundation
If you're new to IV therapy or want to assess your baseline response before committing to a full NAD⁺ loading protocol, a single Myers Cocktail session provides a comprehensive starting point with measurable benefit on its own.
Start With MyersWHY DRIPDOK
A Physician-Founded System. Not an IV Menu.
DripDok was established in 2017 by a US-trained physician with academic foundations in molecular genetics, analytical chemistry, and biotechnology — and is associated with research through Purdue, Harvard, MIT, and Michigan State University. As the first clinic in Southeast Asia to offer advanced NAD+ IV protocols, DripDok operates as a precision medicine system, not a retail infusion bar. Every protocol is governed by diagnostic-first methodology, cold-chain sourcing standards, and formal physician oversight — applied to every client, every session.
PERSONALISED PROTOCOL
Experiencing Fatigue That Doesn't Resolve With Rest?
NAD⁺ depletion presents differently depending on age, metabolic history, and lifestyle load. Dr. Close reviews your intake data to determine whether a standard loading protocol applies — or whether your situation calls for a modified approach to frequency, volume, or adjunctive support.
Dr. Close reviews all intake forms personally. Consultations are conducted via teleconsult or in person in Bali.
BEGIN YOUR PROTOCOL
How to Book a Session
Your Patient Relations team coordinator reviews your request and sends a secure payment link via Wise, Stripe, or local transfer. After payment, you complete a medical intake and consent form. Your physician reviews it for clinical suitability, then confirms your appointment. Standard protocols require 24–48 hours advance notice for nurse scheduling and cold-chain preparation.